- Support for healthy blood sugar metabolism and cholesterol maintenance
- Contains berberine for cardiometabolic health support
- Contains grape seed extract, a well known antioxidant, for heart health support
- Contains alpha lipoic acid to support proper insulin function
- Antioxidant support
Polyphenols, part of a broad class of bioflavonoids, are commonly found in grape seeds. One type of polyphenols known as proanthocyanidins is highly regarded for their strong antioxidant properties, and for their functions in supporting the capillaries. Proanthocyanidins appear to be especially useful support in neutralizing highly reactive hydroxyl and singlet oxygen radicals.
Alpha lipoic acid is a nutritional coenzyme that is involved in the energy metabolism of proteins, carbohydrates and fats, has physiological functions in blood glucose clearance, and is able to support scavenging a number of free radicals. This important coenzyme appears to be necessary for the normal transport of blood glucose into the cell. This may be explained by its functions in the glucose-metabolizing enzymes, PDH and alpha-KGDH, but some researchers suspect a more direct role in cellular glucose uptake at the cell membrane.
For natural blood sugar and cholesterol support, try Berberine Balance today!
1 vegetarian capsule contains:
Berberine HCl 500mg
---(from Berberis aristata extract, root)
Alpha lipoic acid 50mg
Grape Seed extract 50mg
Other Ingredients: Cellulose, dicalcium phosphate, vegetable stearate and silica.
Adults: As a dietary supplement, adults take 1 capsule twice daily or as directed by your healthcare professional.
May cause gastrointestinal adverse effects in some individuals. Berberine may increase bilirubin levels. Berberine displaces bilirubin from albumin and increases total and unbound bilirubin concentrations. Berberine appears to undergo phase I hepatic metabolism. There is preliminary evidence that berberine might inhibit cytochrome P450 3A4, 2C9, 2D6 enzymes. Therefore, watch for an increase in the levels of drugs metabolized by these enzymes in patients taking berberine. DO NOT TAKE IF PREGNANT OR LACTATING. Keep out of the reach of children.
REFERENCES Yifei Zhang, et al. Treatment of Type 2 Diabetes and dyslipidemia with the natural plant alkaloid berberine. J. Clin. Endocrinol. Metab. published online Apr 8, 2008; , doi: 10.1210/jc.2007-2404 Jun Yina, Huili Xing, and Jianping Yeb. Efficacy of Berberine in Patients with Type 2 Diabetes. Metabolism. 2008 May ; 57(5): 712GÇô717.
GUO Yi. Biochemical pathways in the antiatherosclerotic effect of berberine. Chinese Medical Journal 2008; 121(13):1197-1203
Kong W, et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med. 2004 Dec;10(12):1344-51.
Zeng XH, Zeng XJ, Li YY. Efficacy and safety of berberine for congestive heart failure secondary to ischemicor idiopathic dilated cardiomyopathy. Am J Cardiol 2003;92:173-6
Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay, and mode of action. Can J Microbiol 1969;15:1067-76.
Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. Jacob S, Henriksen EJ, Schiemann AL, et al. Enhancement of glucose disposal in patients with Type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45:872-874.
Kamenova P. Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alpha-lipoic acid. Hormones (Athens). 2006 Oct-Dec;5(4):251-8.
Robert L et al: Action of procyanidolic oligomers on vascular permeability. Path Biol 1990;38:608-616.
Bagchi D, Bagchi M, Stohs SJ, et al. Cellular protection with proanthocyanidins derived from grape seeds.Ann N Y Acad Sci 2002;957:260-70