SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine.

SAM-e has undergone dozens of trials involving thousands of patients and its benefits to the body include:

Joint Strength - SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites

Brain Metabolism - SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin)

Longevity - Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity

Liver - SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function

Jarrow Formulas SAM-e 400 is a stabilized, pharmaceutical grade, stabilized product that is enteric-coated to ensure a biologically active product.

Ingredients:
Full Potency 400 mg elemental SAM-e is derived from 800 mg of tosylate disulfate SAM-e.
Other Ingredients: Microcrystalline cellulose, enteric coating (methacrylate copolymers), glycerol behenate, talc, triethylcitrate, glycerol palmitostearate, medium chain triglycerides, silicon dioxide, titanium dioxide, magnesium stearate and yellow iron oxide. Suitable for vegetarians. This product complies with the proposed USP Monograph for SAM-e.

Recommended Use:
Adults: Take 1 tablet per day on an empty stomach, or as directed by your qualified health consultant.

Warning:
Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and MAO Inhibitors should consult a physician before using. Individuals with Parkinsons disease, bi-polar disorder or manic depression should not use SAM-e.