Cran-C-Plex capsules, provided by Douglas Laboratories®, contain a natural concentrate of cranberry juice with additional vitamin C. Cran-C-Plex capsules may be a beneficial nutritional supplement for individuals who wish to enhance urinary tract health through the natural benefits of this cranberry juice concentrate.

Cranberry juice has been recognized over the past few decades for its useful role in supporting urinary tract health. Initially its beneficial properties were attributed to its ability to acidify urine due to its content of organic acids, such as benzoic, malic, quinic, ellagic, shikimic, and citric acids. Metabolism of benzoic acid presumably produces a significant amount of hippuric acid, suggested to be bacteriostatic for Escherichia coli.

Nevertheless, recent research indicates that other mechanisms may be responsible. These bioactive components of the cranberry (Vaccinium macrocarpon) may support the urinary tract by inhibiting adherence of pathogenic bacteria to urinary epithelial cells and their subsequent proliferation and infection.

Bacteria can adhere to epithelial cells via molecules called adhesins, produced by fimbriae, proteinaceous fibers on the bacterial cell surface. It appears that two components of cranberry inhibit bacterial adhesion: fructose and proanthocyanidins.

Fructose, a sugar typically found in fruit, has been suggested to inhibit adherence of E. coli with type 1 fimbriae, while cranberry proanthocyanidins have been shown to prevent P-fimbriated E. coli from adhering to urinary tract cells. The vitamin C in Cran-C-Plex augments the natural antioxidant power of these proanthocyanidins.

Ingredients:
Each Capsule Contains:
Vitamin C 100 mg
Cranberry Juice 140 mg
(Natural Concentrate)
Other Ingredients: gelatin (capsule), water.
Contains NO: yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Recommended Use:
Adults: take 1 capsule daily or as directed by physician.

Warning:
Keep out of the reach of children.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.